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Substance use, abuse, and addiction. It can range from mild. Web drug addiction, also called substance use disorder, is a disease that affects a person's brain and behavior and. Web since sud is a complex brain disorder, it is difficult to pinpoint the exact moment when drug use becomes a substance abuse. Web abuse of substances impairs the ability to regulate emotions, as the substance takes on the protective,. Web substance use disorder (sud) is a complex condition that involves a problematic pattern of substance use. Web notes to self. The 11 symptoms of substance use disorders.